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Image Number #393 (Lymphoma CD30+ anaplastic large cell)

Diagnosis: Lymphoma CD30+ anaplastic large cell

Description: Nodules on the lower limbs

Clinical Features: Nodule

Pathology/Site Features: Tumour cells in dermis

Sex: M

Age: 55

Submitted By:

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Differential Diagnosis
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History: This 55-year-old male presented with multiple asymptomatic nodules mainly on the extremities some of which are ulcerated of 6 months duration. Biopsy of one of the lesions reported diffuse infiltration of large atypical lymphoid cells with pleomorphic nuclei, eosinophilic cytoplasm & frequent mitotic figures. The infiltration goes deeply replacing the subcutaneous tissue. Immunohistochemical studies showed the cells to be positive for LCA, CD3 and CD30 but negative for CD20.

DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Lymphoma CD30+ anaplastic large cell"

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