Diagnosis: Sweet's Syndrome
Description: Note the sub epidermal oedema with a neutrophilic infiltrate
Clinical Features: Nodule,skin coloured
Pathology/Site Features: Edema of the dermis
Sex: M
Age: 55
Submitted By: Ian McColl
Differential Diagnosis
History: Sudden onset of a nodular eruption on the arms in a man suffering from Rheumatoid arthritis with a RF titre of greater than 4000. He had recently had his methotrexate ceased because of a pyrexia of unknown origin.
See this recent review of Sweets Syndrome