Diagnosis: Trichilemmoma
Description:
Clinical Features: Nodule pink
Pathology/Site Features: Face
Sex: M
Age: 54
Submitted By: Ian McColl
Differential DiagnosisHistory:
Trichilemmoma Clinical Multiple or single warty like papules on the face or keratoses on the hands and feet . On the face they are congregated around the mouth, nose or ears and can be associated with Cowden's disease ( multiple hamartomas and marked risk of breast and thyroid carcinomas.). Intraoral papules on the tongue (cobblestoning) are also a feature.
Trichilemmoma - This shows a warty surface with lobular proliferation of polygonal cells with clear cell change and peripheral palisading, apoptotic bodies and lobules bounded by an eosinophilic basement membrane . Note association with Cowden syndrome. Virtual Slide
View this video from Joel Gardner Another video from Ian mcColl