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Image Number #1033 (Acneiform eruption)

Diagnosis: Acneiform eruption

Description: A composite of clinical images of acneiform pathology

Clinical Features: Pustules

Pathology/Site Features: Face

Sex: M

Age: 23

Submitted By: Ian McColl

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Differential Diagnosis

History:

Chloracne is an unusual condition associated with exposure to chlorinated hydrocarbons. It usually presents as multiple comedones in areas where you don’t expect to see comedones, e.g. the forearms, the neck and the shoulders. Histopathology shows dilated follicular infundibula with multiple comedones and follicular cysts. The degree of inflammation is quite variable. The features may be similar to acne, but sometimes there is an absence of sebaceous glands.

Pseudofolliculitis barbae is due to ingrowing hairs, usually because of a genetic tendency to have curved hairs, particularly seen in African Americans. Granulomas may be seen as a foreign body type reaction with parts of hairs showing transepidermal elimination.

Acne keloidalis isn’t really a variant of acne. It is a type of staph folliculitis, particularly seen around the back of the neck, in African Americans and associated with scarring.
Virtual Slide Histology will show abscesses adjacent to hair follicles. Sometimes there are more plasma cells seen. Ultimately there is dermal fibroplasia and scarring with destruction of hair follicles.

Halogenoderma   This is a rare case of a pustular acneiform rash but it can be seen in renal failure when lots of scans are done using iodine and when people takes excessive iodine supplements. Virtual Slide at Path Presenter

DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Acneiform eruption"

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