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Image Number #860 (Discoid lupus erythematosus)

Diagnosis: Discoid lupus erythematosus

Description: Biopsies of skin in which there is a lichenoid reaction involving the epidermis and follicular epithelium. This is accompanied by a superficial and mid dermal perivascular and perifollicular infiltrate of lymphocytes

Clinical Features: Red,scaly

Pathology/Site Features: Periadnexal infiltrate

Sex: F

Age: 30

Submitted By: Ian McColl

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Differential Diagnosis
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History: 4826kh Two year history of indurated areas on both lower eyelids followed by plaques x 2 on both cheeks. No steroid creams used as far as I can ascertain. DD Discoid lupus, sarcoidosis or necrobiotic xanthogranuloma. Biopsies cheek plaque and lower eyelid

Description: Folliculo-centric lichenoid reaction

Comments: Sections show a biopsies of skin in which there is a lichenoid reaction involving the epidermis and follicular epithelium. This is accompanied by a superficial and mid dermal perivascular and perifollicular infiltrate of lymphocytes. There is thickening of the epidermal basement membrane and some overlying ortho- and parakeratosis. The changes are those of discoid lupus erythematosus.

DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Discoid lupus erythematosus"

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