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Image Number #843 (Subacute lupus erythematosus)

Diagnosis: Subacute lupus erythematosus

Description: Red non scaly annular rash back

Clinical Features: Annular

Pathology/Site Features: Back

Sex: F

Age: 78

Submitted By: Ian McColl

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Differential Diagnosis
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History: 2239mr Recent case previously thought to be a drug reaction with impetiginisation but when dose of steroids reduced this rash came up. Previous immunofluorescence negative. DD Lupus erythematosus, still drug reaction, drug induced lupus?

Description: Lichenoid dermatitis

Comments: Sections show biopsies of skin in which there is a lichenoid reaction present. There is thinning of the epidermis with basal epidermal vacuolar change and quite prominant Civatte bodies. There is overlying patchy parakeratosis. There is a mild to moderate superficial and mid dermal perivascular infiltrate of lymphocytes. These features best fit for a subacute type of lupus erythematosus.

DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Subacute lupus erythematosus"

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